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Plasma kallikrein-IN-3

CAS: 1357950-47-0 F: C20H23N5O2 W: 365.43

Plasma kallikrein-IN-3 is a plasma kallikrein inhibitor (IC50: 0.15 μM). Plasma kallikrein-IN-3 can be used for heredit
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Plasma kallikrein-IN-3 is a plasma kallikrein inhibitor (IC50: 0.15 μM). Plasma kallikrein-IN-3 can be used for hereditary angioedema, diabetic macular edema, and diabetic retinopathy research[1].
Target Plasma kallikrein
Invitro Plasma kallikrein-IN-3 (example 13, 1 nM-100 μM, 1 h) inhibits plasma kallikrein activity with an IC50 value of 0.15 μM[1].
Name Plasma kallikrein-IN-3
CAS 1357950-47-0
Formula C20H23N5O2
Molar Mass 365.43
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Brandl Trixi, et al. Preparation of N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides as inhibitors of plasma kallikrein. Patent WO2012017020.