| Bioactivity | Plafibride (ITA 104) is an orally active hypolipemic, platelet aggregation inhibitor[1][2]. |
| In Vivo | Plafibride (100 mg/kg, p.o.) shows marked platelet anti-aggregant activity[1].Plafibride has low toxicity, with LD50s of about 4000 mg/kg (p.o.) in rat, mouse and hamster[2]. Animal Model: |
| Name | Plafibride |
| CAS | 63394-05-8 |
| Formula | C16H22ClN3O4 |
| Molar Mass | 355.82 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. L Bruseghini, et al. Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittelforschung. 1981;31(10a):1790-5. [2]. J Zapatero, et al. Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittelforschung. 1981;31(10a):1816-9. |