| Bioactivity | Pks13-IN-1 (Compound 44) is an orally active inhibitor for Mycobacterium tuberculosis Polyketide synthase 13 (Pks13). Pks13-IN-1 inhibits M. tuberculosis strain H37Rv with a MIC of 0.07 μM. Pks13-IN-1 exhibits antibacterial efficacy in mouse model[1]. |
| Formula | C20H17BrN4O2 |
| Molar Mass | 425.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang X, et al., Structure-based development of N-Arylindole derivatives as Pks13 inhibitors against Mycobacterium tuberculosis. Eur J Med Chem. 2025 Feb 5;283:117148. |