| Bioactivity | PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL)[1]. |
| Target | IC50: 14.4 μM (PknB) |
| Invitro | PknB-IN-1 (0-100 μM; 60 min) can inhibit M. tuberculosis PknB activity[1]. Cell Viability Assay[1] Cell Line: |
| Name | PknB-IN-1 |
| CAS | 1447917-39-6 |
| Formula | C25H30N2O2 |
| Molar Mass | 390.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Paptawan Thongdee, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22. |
PknB-IN-1
CAS: 1447917-39-6 F: C25H30N2O2 W: 390.52
PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM). PknB-IN-1 shows anti-mycobacterial activi
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.