Piroxicam cinnamate_product_DataBase

Bioactivity	Piroxicam cinnamate (Cinnoxicam) is a cyclooxygenase (COX) inhibitor, with anti-inflammatory activity. Piroxicam cinnamate is stable under gastric conditions, can be used for inflammatory-degenerative osteoarticular diseases, rheumatic disorders, and varicocele (VC) associated oligoasthenospermia research[1][2][4].
In Vivo	Piroxicam cinnamate decreases plantar edema induced by egg's white in the rat's hind paw[3].
Name	Piroxicam cinnamate
CAS	87234-24-0
Formula	C24H19N3O5S
Molar Mass	461.49
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Poli G, et al. The Role of NLRP3 Inflammasome Activation and Oxidative Stress in Varicocele-Mediated Male Hypofertility. Int J Mol Sci. 2022 May 7;23(9):5233. [2]. Cavallini G, et al. Medical therapy of oligoasthenospermia associated with left varicocele. BJU Int. 2003 Apr;91(6):513-8. [3]. Berti M, et al. [Correlation of the lipophilicity of the active agents with their topical anti-inflammatory activity]. Bollettino Chimico Farmaceutico, 1992, 131(7):270-273. [4]. M Nakka, et al. Synthesis, characterization and anti-bacterial screening of Piroxicam based sulfonates. J. Chem. Pharm. Res., 2011, 3(2):581-588.

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