| Bioactivity | Piprofurol is a calcium channel inhibitor. Piprofurol inhibites in a concentration-dependent manner the calcium-induced contractions in isolated potassium depolarized preparations of rat aorta and relaxes the K+-induced contraction of the dog coronary artery and the rabbit basilar artery. Piprofurol exerts a negative inotropic effect on guinea-pig papillary muscle, with the EC50 of 5 μM[1]. |
| Target | 5 μM(guinea-pig papillary muscle) |
| Name | Piprofurol |
| CAS | 40680-87-3 |
| Formula | C26H33NO6 |
| Molar Mass | 455.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pourrias B, et al. Calcium blocking properties of piprofurol. Arch Int Pharmacodyn Ther. 1985;274(2):223-239. |