Bioactivity | Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani[1]. |
Invitro | Piperolactam A 对杜氏利什曼原虫野生型、耐药和野外分离的无菌无鞭毛体细胞系具有抑制活性,IC50 值为 60 ± 9.6 μM (野生型),分别为 121 ± 18 μM (抗 SSG)、109 ± 15 μM (抗 PMM) 和 87 ± 12 μM (野外分离株)[1]。 |
Name | Piperolactam A |
CAS | 112501-42-5 |
Formula | C16H11NO3 |
Molar Mass | 265.26 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bhattacharya P, et al. In Vitro susceptibilities of wild and drug resistant Leishmania donovani amastigotes to piperolactam A loaded hydroxypropyl-β-cyclodextrin nanoparticles. Acta Trop. 2016 Jun;158:97-106. |