Pipernonaline

CAS: 88660-10-0 F: C21H27NO3 W: 341.44

Pipernonaline is a piperine derivative with antiprostate cancer activity. Pipernonaline inhibits the proliferation of an

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Bioactivity	Pipernonaline is a piperine derivative with antiprostate cancer activity. Pipernonaline inhibits the proliferation of androgen-dependent/independent LNCaP/PC-3 prostate cells. Pipernonaline activates caspase-3 and promotes procaspase-3/PARP cleavage. Pipernonaline also mediates reactive oxygen species (ROS) production, increased intracellular Ca(2+), and mitochondrial membrane depolarization[1].
Name	Pipernonaline
CAS	88660-10-0
Formula	C21H27NO3
Molar Mass	341.44
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Lee W, et al. Pipernonaline from Piper longum Linn. induces ROS-mediated apoptosis in human prostate cancer PC-3 cells. Biochem Biophys Res Commun. 2013 Jan 4;430(1):406-12..

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