| Bioactivity | Piperazine (1,4-Diazacyclohexane) is a gamma-aminobutyric acid (GABA) agonist[1]. Piperazine is a vital building block and is an essential core in numerous marketed drugs with diverse pharmacological activities[2]. | ||||||||||||
| Name | Piperazine | ||||||||||||
| CAS | 110-85-0 | ||||||||||||
| Formula | C4H10N2 | ||||||||||||
| Molar Mass | 86.14 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Lovell RA. Ivermectin and piperazine toxicoses in dogs and cats. Vet Clin North Am Small Anim Pract. 1990;20(2):453-468. [2]. Girase PS, et al. An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review. Eur J Med Chem. 2021;210:112967. [3]. Jain A, et al. Piperazine: A Promising Scaffold with Analgesic and Anti-inflammatory Potential. Drug Res (Stuttg). 2021;71(2):62-72. [4]. Kumar RR, et al. Piperazine, a Key Substructure for Antidepressants: Its Role in Developments and Structure-Activity Relationships. ChemMedChem. 2021;16(12):1878-1901. |