| Bioactivity | Pinealon is a 3-amino acid peptide and shows neuroprotective properties. Pinealon prevents reactive oxygenspecies (ROS) accumulation and supressesthe activation of ERK 1/2. Pinealon has the ability to stimulate the functional activity of the main cellular elements of brain tissue, reduce the level of spontaneous cell death. Pinealon protects the rat offspring from prenatal hyperhomocysteinemia[1][2][3]. |
| Invitro | Pinealon (10, 50, 100 nM; 30 min) 以剂量依赖性方式阻止哇巴因诱导的小脑颗粒细胞中 ROS 积累的增加[1]。Pinealon (10 nM; 0, 2.5, 5, 10, 20, 30 min) 抑制暴露于 500 mM 同型半胱氨酸 (HC) 的大鼠小脑颗粒细胞中 ERK 1/2 的激活[1]。 |
| Name | Pinealon |
| CAS | 175175-23-2 |
| Shortening | EDR |
| Formula | C15H26N6O8 |
| Molar Mass | 418.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |