Bioactivity | Pim-1 kinase inhibitor 11 (10f) is a PIM-1 inhibitor, with an IC50 of 0.18 μM. Pim-1 kinase inhibitor 11 (10f) exhibits anticancer activity. Pim-1 kinase inhibitor 11 (10f) induces apoptosis and arrests cell cycle progression[1]. |
Invitro | Pim-1 kinase inhibitor 11 (10f) 具有显著的抗癌活性,尤其是 A-549 细胞系 (IC50 范围: 1.28-3.52 μM)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Pim-1 kinase inhibitor 11 相关抗体: |
Formula | C27H20N4O |
Molar Mass | 416.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wagdy M Eldehna, et al. Identification of indole-grafted pyrazolopyrimidine and pyrazolopyridine derivatives as new anti-cancer agents: Synthesis, biological assessments, and molecular modeling insights. Bioorg Chem. 2024 Sep 6:153:107804. |