PeptideDB

Pim-1 kinase inhibitor 11

CAS: F: C27H20N4O W: 416.47

Pim-1 kinase inhibitor 11 (10f) is a PIM-1 inhibitor, with an IC50 of 0.18 μM. Pim-1 kinase inhibitor 11 (10f) exhibits
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Bioactivity Pim-1 kinase inhibitor 11 (10f) is a PIM-1 inhibitor, with an IC50 of 0.18 μM. Pim-1 kinase inhibitor 11 (10f) exhibits anticancer activity. Pim-1 kinase inhibitor 11 (10f) induces apoptosis and arrests cell cycle progression[1].
Invitro Pim-1 kinase inhibitor 11 (10f) 具有显著的抗癌活性,尤其是 A-549 细胞系 (IC50 范围: 1.28-3.52 μM)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Pim-1 kinase inhibitor 11 相关抗体:
Formula C27H20N4O
Molar Mass 416.47
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Wagdy M Eldehna, et al. Identification of indole-grafted pyrazolopyrimidine and pyrazolopyridine derivatives as new anti-cancer agents: Synthesis, biological assessments, and molecular modeling insights. Bioorg Chem. 2024 Sep 6:153:107804.