Bioactivity | Picosulfate sodium salt hydrate is the hydrate of Sodium Picosulfate (HY-B0544). Picosulfate sodium salt hydrate is an orally active contact irritant laxative. Picosulfate sodium salt hydrate inhibits the absorption of water and electrolytes, increasing their production. Picosulfate sodium salt hydrate can be used in colonoscopy applications[1][2][3][4]. |
CAS | 1307301-38-7 |
Formula | C18H15NNa2O9S2 |
Molar Mass | 499.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Nishikawa J, et al. Toxicity study with sodium picosulfate in cultured liver cells of rabbit, rat and man. Arzneimittelforschung. 1981;31(2):321-5. [2]. Geboes K, et al. Effects of 'contact laxatives' on intestinal and colonic epithelial cell proliferation. Pharmacology. 1993 Oct;47 Suppl 1:187-95. [3]. Fioramonti J, et al. In vivo motility of rat colon chronically pretreated with sennosides. Pharmacology. 1993 Oct;47 Suppl 1:155-61. [4]. Regev A, et al. Comparison of two bowel preparations for colonoscopy: sodium picosulphate with magnesium citrate versus sulphate-free polyethylene glycol lavage solution. Am J Gastroenterol. 1998 Sep;93(9):1478-82. |