Phytoene desaturase-IN-1_product_DataBase

Bioactivity	Phytoene desaturase-IN-1 is a potent phytoene desaturase (PDS) inhibitor (Kd: 65.9 μM) through π−π stacking effect with Phe301 residue. Phytoene desaturase-IN-1 shows broad spectrum of postemergence herbicidal activity. Phytoene desaturase-IN-1 induces PDS mRNA reduction, phytoene and reactive oxygen species (ROS) accumulation in albino leaves. Phytoene desaturase-IN-1 can be used in the area of agricultural production[1].
Target	Phytoene desaturase (PDS), reactive oxygen species (ROS).
Invitro	Phytoene desaturase-IN-1 (1b, 375−750 g/ha, 25 days) shows a broad spectrum of herbicidal activity against six kinds of weeds (including ECHCG, DIGSA, SETFA, ABUJU, AMARE, and ECLPR)[1].Phytoene desaturase-IN-1 (750 g/ha, 14 days) down-regulates PDS mRNA level and induces phytoene accumulation, with the observed albino leaf phenotype[1].Phytoene desaturase-IN-1 (750 g/ha, 3 days) induces ROS accumulation and regulates ROS-associated enzymes activity[1]. RT-PCR[1] Cell Line:
Name	Phytoene desaturase-IN-1
CAS	2765793-54-0
Formula	C18H13ClF3N3O2S
Molar Mass	427.83
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Di Zhang, et al. Discovery of (5-(Benzylthio)-4-(3-(trifluoromethyl)phenyl)-4 H-1,2,4-triazol-3-yl) Methanols as Potent Phytoene Desaturase Inhibitors through Virtual Screening and Structure Optimization. J Agric Food Chem. 2022 Aug 10.

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