| Bioactivity | Physapubenolide is a cytotoxic steroidal compound isolated from Physalis, which has the activity of increasing intracellular ROS levels by downregulating TIGAR, thereby inducing apoptosis and autophagosome formation in human breast cancer cells, ultimately inhibiting tumor growth. |
| CAS | 100217-92-3 |
| Formula | C30H40O8 |
| Molar Mass | 528.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway [2]. Downregulation of TIGAR sensitizes the antitumor effect of physapubenolide through increasing intracellular ROS levels to trigger apoptosis and autophagosome formation in human breast carcinoma cells |
Physapubenolide
CAS: 100217-92-3 F: C30H40O8 W: 528.63
Physapubenolide is a cytotoxic steroidal compound isolated from Physalis, which has the activity of increasing intracell
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