| Bioactivity | Phyltetralin (Compound 10) is a natural product than can be isolated from the hexane-ethyl acetate extract of Phyllanthus amarus leaves. Phyltetralin possesses immunosuppressive effects on different lineages of innate immune system[1][2]. |
| Invitro | Phyltetralin shows inhibition on Polymorphonuclear neutrophil (PMN) chemotaxis with an IC50 of 4.01 µM[2].Phyltetralin shows strong inhibition against reactive oxygen species (ROS) production from PMA-stimulated neutrophil with an IC50 of 0.73 µM[2].Phyltetralin shows weak inhibition on CD18 expression and moderate inhibition on engulfment activity[2]. |
| Name | Phyltetralin |
| CAS | 123048-17-9 |
| Formula | C24H32O6 |
| Molar Mass | 416.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Conrado GG, et al. Prospecting and Identifying Phyllanthus amarus Lignans with Antileishmanial and Antitrypanosomal Activity. Planta Med. 2020 Jul;86(11):782-789. [2]. Yuandani, et al. 1, 7, 8-trihydroxy 2-naphtaldehyde, ethyl 8-hydroxy-8-methyl-tridecanoate and 1-triacontanol from Phyllanthus amarus Schumach. & Thonn. inhibit phagocytic activity of human leucocytes[J]. Journal of Pharmacy and Pharmacology, 2019, 71(9): |
Phyltetralin
CAS: 123048-17-9 F: C24H32O6 W: 416.51
Phyltetralin (Compound 10) is a natural product than can be isolated from the hexane-ethyl acetate extract of Phyllanthu
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