| Bioactivity | Phosphorylated CHKtide is a synthetic peptide substrate derived from CDC25C, which is phosphorylated by CHK1/CHK2 in one of the DNA repair pathways. Phosphorylated CHKtide is used in the assays of cell cycle checkpoint kinases 1 and 2 (CHK1/CHK2) and salt-inducible kinases (SIKs)[1]. |
| Sequence | Lys-Lys-Lys-Val-{pSer}-Arg-Ser-Gly-Leu-Tyr-Arg-Ser-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg |
| Shortening | KKKV-{pSer}-RSGLYRSPSMPENLNRPR |
| Formula | C115H199N40O36PS |
| Molar Mass | 2781.10 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yoshida, et al. Phosphorylation of microtubule‐associated protein tau by AMPK‐related kinases. Journal of neurochemistry 120.1 (2012): 165-176. |
Phosphorylated CHKtide
CAS: F: C115H199N40O36PS W: 2781.10
Phosphorylated CHKtide is a synthetic peptide substrate derived from CDC25C, which is phosphorylated by CHK1/CHK2 in one
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