| Bioactivity | Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a phosphatidate phosphatase (Pah) inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads[1]. |
| Invitro | Phosphatase-IN-1 (compound II-8) 在 223 60 µM 浓度下可有效抑制八种植物病原体的营养生长[1]。与野生菌株相比，Phosphatase-IN-1 (compound II-8) 对 Mopah1 突变体的抑制作用减弱[1]。 0 --> Phosphatase-IN-1 相关抗体: |
| Name | Phosphatase-IN-1 |
| CAS | 2889356-55-0 |
| Formula | C16H16Cl2FNO2 |
| Molar Mass | 344.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao J, et al. Identification of propranolol and derivatives that are chemical inhibitors of phosphatidate phosphatase as potential broad-spectrum fungicides. Plant Commun. 2023 Aug 30:100679. |
Phosphatase-IN-1
CAS: 2889356-55-0 F: C16H16Cl2FNO2 W: 344.21
Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a phosphatidate phosphatase (Pah) inhibitor.
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This product is for research use only, not for human use. We do not sell to patients.