Bioactivity | Phomopsinamine A is a derivative of Phomopsin A (HY-N6793). Phomopsinamine A is an inhibitor for tubulin polymerization with IC50 of 0.53 μM. Phomopsinamine A inhibits the binding of Vinblastine (HY-13780) to tubulin (IC50 =0.56 μM), promotes the the binding of Colchicine (HY-16569) to tubulin (IC50 =0.32 μM)[1]. |
CAS | 89085-54-1 |
Formula | C32H43ClN6O8 |
Molar Mass | 675.17 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lacey E, et al., Interaction of phomopsin A and related compounds with purified sheep brain tubulin. Biochem Pharmacol. 1987 Jul 1;36(13):2133-8. |