| Bioactivity | Phenylpiracetam(Phenotropyl; Phenotropil) is a phenylated derivative of the nootropic drug piracetam. It is used as a stimulant nootropic drug that can be up to 30-60 times more potent than piracetam.IC50 Value:Target: AMPA receptor allosteric modulatorin vitro: N/Ain vivo: In the open-field test, a significant increase in locomotor activity was observed after a single administration of R-phenotropil at doses of 10 and 50 mg/kg and S-phenotropil at a dose of 50 mg/kg. In the forced swim test, R-phenotropil induced an antidepressant effect at doses of 100 and 50 mg/kg, and S-phenotropil was active at a dose of 100 mg/kg. R-phenotropil significantly enhanced memory function in a passive avoidance response test at a dose of 1 mg/kg; the S-enantiomer did not show any activity in this test [1]. | ||||||||||||
| Name | Phenylpiracetam | ||||||||||||
| CAS | 77472-70-9 | ||||||||||||
| Formula | C12H14N2O2 | ||||||||||||
| Molar Mass | 218.25 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Zvejniece L, et al. Investigation into stereoselective pharmacological activity of phenotropil. Basic Clin Pharmacol Toxicol. 2011 Nov;109(5):407-12. |
Phenylpiracetam
CAS: 77472-70-9 F: C12H14N2O2 W: 218.25
Phenylpiracetam(Phenotropyl; Phenotropil) is a phenylated derivative of the nootropic drug piracetam. It is used as a st
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