Bioactivity | Phenaglycodol belongs to the group of butanediolsa with anxiolytic and anticonvulsant porperties. Phenaglycodol has orally bioactivity[1]. |
In Vivo | Phenaglycodol (20 mg/kg, 腹腔注射,1次) 对猫有抗癫痫作用[1]。Phenaglycodol (55-80 mg /kg, 腹腔注射, 1次) 对小鼠有抗癫痫作用[1]。Phenaglycodol (50-100 mg/kg, 灌胃, 1次) 对猴子有抗癫痫作用[1]。Phenaglycodol (130 mg/kg, 腹腔注射, 1次) 可降低血清和脑中Meprobamate 的浓度[2]。 Animal Model: |
Name | Phenaglycodol |
CAS | 79-93-6 |
Formula | C11H15ClO2 |
Molar Mass | 214.69 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. G T JONES, et al. Mode of action of phenaglycodol, a new neurosedative agent. Proc Soc Exp Biol Med. 1956 Dec;93(3):528-31. [2]. R. KATO, et al. Induced Increase o f M eprobam ate M etabolism in R ats T reated w ith P hénobarbital or Phenaglycodol. Pharmacology (1970) 3 (2): 95–100. |