| Bioactivity | Pfn1-IN-2 is an inhibitor of Profilin1 (Pfn1) and has the activity to interfere with the interaction between Pfn1 and actin. Pfn1-IN-2 can significantly reduce the overall level of intracellular filamentous (F) actin. Pfn1-IN-2 also slows down the migration and proliferation of endothelial cells (EC). Pfn1-IN-2 can inhibit the angiogenic ability of endothelial cells both in vivo and in vitro[1]. |
| CAS | 919010-22-3 |
| Formula | C18H13N7O2 |
| Molar Mass | 359.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Structure-based virtual screening identifies a small-molecule inhibitor of the profilin 1-actin interaction |
Pfn1-IN-2
CAS: 919010-22-3 F: C18H13N7O2 W: 359.34
Pfn1-IN-2 is an inhibitor of Profilin1 (Pfn1) and has the activity to interfere with the interaction between Pfn1 and ac
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