| Bioactivity | PfThrRS-IN-1 (compound 11) is a potent inhibitor of Plasmodium falciparum threonyl tRNA synthetase (PfThrRS), with the IC50 value of 0.1 μM. PfThrRS-IN-1 is a potent antimalaria agent[1]. |
| Target | 0.1 μM (PfThrRS) |
| Name | PfThrRS-IN-1 |
| Formula | C15H16N6O4S2 |
| Molar Mass | 408.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jekaterina Bolsakova, et al. Discovery of Malarial Threonyl tRNA Synthetase Inhibitors by Screening of a Focused Fragment Library. December 2023 ACS Medicinal Chemistry Letters |