| Bioactivity | PfPKG-IN-2 (compound 53) is a potent Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) inhibitor with an IC50 value of 13 nM. PfPKG-IN-2 shows antiparasitic activity[1]. |
| Target | IC50:13 nM (PfPKG) |
| Formula | C22H24FN3 |
| Molar Mass | 349.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gilleran JA, et al. Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials. J Med Chem. 2024 Feb 19. |