| Bioactivity | PfFAS-II inhibitor 1 (Compound 3) is a Plasmodium falciparum type II fatty acid biosynthesis pathway (PfFAS-II) inhibitor, with an IC50 of 0.63 μM for PfFabI enzyme. PfFAS-II inhibitor 1 has antimalarial activity[1]. |
| Target | Plasmodium falciparum Type II Fatty Acid Biosynthesis Pathway (PfFAS-II) |
| CAS | 1459704-68-7 |
| Formula | C15H9ClO4 |
| Molar Mass | 288.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Belluti F, et al. Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI). J Med Chem. 2013 Oct 10;56(19):7516-26. |
PfFAS-II inhibitor 1
CAS: 1459704-68-7 F: C15H9ClO4 W: 288.68
PfFAS-II inhibitor 1 (Compound 3) is a Plasmodium falciparum type II fatty acid biosynthesis pathway (PfFAS-II) inhibito
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