| Bioactivity | Perillic acid is the metabolite of Perillyl alcohol (HY-N7000). Perillic acid induces lung cancer cell cycle arrest and apoptosis. Perillic acid shows anti-HSV-1 and immunomodulatory activities[1][2][3]. |
| Invitro | Perillic acid (1-5 mM; 24 h) 以剂量依赖的方式降低 A549 细胞的存活率[1]。Perillic acid (1 mM; 24 h) 诱导 A549 细胞 S 期阻滞,诱导 H520 细胞 G2/M 期阻滞[1]。Perillic acid (2 mM; 24 h) 诱导 A549 和 H520 细胞凋亡[1]。Perillic acid (0-50 μM; 24 h) 显示出主要针对 17syn+ HSV-1 的抗病毒活性 (EC50 KOS: 2.84 μM; 17syn+: 1.08 μM)[2]。 Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Perillic acid |
| CAS | 7694-45-3 |
| Formula | C10H14O2 |
| Molar Mass | 166.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |