| Bioactivity | Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95[1][2]. |
| CAS | 375-85-9 |
| Formula | C7HF13O2 |
| Molar Mass | 364.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yijie Zhou, et al. Effect of prenatal perfluoroheptanoic acid exposure on spermatogenesis in offspring mice. Ecotoxicol Environ Saf. 2023 Jul 15:260:115072. [2]. Moon Yi Ko, et al. Differential regulations of neural activity and survival in primary cortical neurons by PFOA or PFHpA. Chemosphere. 2024 Mar:352:141379. |
Perfluoroenanthic acid
CAS: 375-85-9 F: C7HF13O2 W: 364.06
Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact
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