| Bioactivity | Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes[1][2]. | ||||||||||||
| Target | IC50：0.9-4.3 nM (NA) | ||||||||||||
| Name | Peramivir trihydrate | ||||||||||||
| CAS | 1041434-82-5 | ||||||||||||
| Formula | C15H34N4O7 | ||||||||||||
| Molar Mass | 382.45 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Babu YS, et al. BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design. J Med Chem. 2000 Sep 21;43(19):3482-6. [2]. Young D, et al. RWJ-270201 (BCX-1812): a novel neuraminidase inhibitor for influenza. Philos Trans R Soc Lond B Biol Sci. 2001 Dec 29;356(1416):1905-13. |
Peramivir trihydrate
CAS: 1041434-82-5 F: C15H34N4O7 W: 382.45
Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active in
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