| Bioactivity | Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor. | ||||||
| Invitro | Peptide T acts to block viral entry as it inhibits in the MAGI cell assay and blocks infection in the luciferase reporter assay using HIV virions pseudotyped with ADA envelope. Peptide T selectively inhibits HIV replication using chemokine receptor CCR5 compared to CXC4[2]. Peptide T at 10-8 M induces IL-10 production by the human Th2 cell line and PBMC. Also peptide T at 10-9 M concentration significantly inhibits IFN-g production by PBMC[3]. | ||||||
| Name | Peptide T | ||||||
| CAS | 106362-32-7 | ||||||
| Sequence | Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr | ||||||
| Shortening | ASTTTNYT | ||||||
| Formula | C35H55N9O16 | ||||||
| Molar Mass | 857.86 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Peptide T
CAS: 106362-32-7 F: C35H55N9O16 W: 857.86
Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for theCD4 receptor and prevents bi
Data collection：peptidedb@qq.com
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