Bioactivity | Peptide A5K acetate is a INF7-TAT derivative and is used for CRISPR RNP delivery into T cells. Peptide A5K acetate effectively promotes the delivery of Cas9 RNP to natural killer (NK) cells[1]. |
Target | IC50: RNP Delivery |
Name | Peptide A5K acetate |
Sequence | Gly-Leu-Phe-Glu-Lys-Ile-Glu-Gly-Phe-Ile-Glu-Asn-Gly-Trp-Glu-Gly-Met-Ile-Asp-Gly-Trp-Tyr-Gly-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg |
Shortening | GLFEKIEGFIENGWEGMIDGWYGYGRKKRRQRR |
Formula | C182H275N55O48S.xC2H4O2 |
Molar Mass | 4033.54 (free acid) |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Dana V Foss, et al. Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nat Biomed Eng. 2023 May;7(5):647-660. |