| Bioactivity | Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease[1][2]. | ||||||
| Invitro | Pepstatin (Pepstatin A) (7 μM; 48 h) affects the intracellular processing of HIV-specific gag protein[2]. | ||||||
| Name | Pepstatin | ||||||
| CAS | 26305-03-3 | ||||||
| Sequence | IsoValeryl-Val-Val-Sta-Ala-Sta-OH | ||||||
| Shortening | IsoVeryl-VV-Sta-A-Sta-OH | ||||||
| Formula | C34H63N5O9 | ||||||
| Molar Mass | 685.89 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |