| Bioactivity | Peniditerpenoid A is a di-seco-indole diterpenoid. Peniditerpenoid A decreases the expression of p-IkBαby RANKL induced. Peniditerpenoid A inhibits RANKL induced osteoclast differentiation. Peniditerpenoid A has the potential for the research of osteoporosis[1]. |
| Invitro | Peniditerpenoid A (compound 1) (5, 10, 20 µM) 以剂量依赖性方式抑制 RANKL 诱导的破骨细胞分化[1]。Peniditerpenoid A (5, 10, 20 µM) 降低 RAW264.7 细胞中 p-IkBα 的表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Peniditerpenoid A 相关抗体: Western Blot Analysis[1] Cell Line: |
| Formula | C27H33NO7 |
| Molar Mass | 483.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cai J, et al. Peniditerpenoids A and B: Oxidized Indole Diterpenoids with Osteoclast Differentiation Inhibitory Activity from a Mangrove-Sediment-Derived Penicillium sp. J Nat Prod. 2024 May 24;87(5):1401-1406. |