| Bioactivity | Penicillin amidase (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics[1][2][3]. |
| Name | Penicillin amidase |
| CAS | 9014-06-6 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Duggleby HJ, et al. Penicillin acylase has a single-amino-acid catalytic centre. Nature. 1995 Jan 19;373(6511):264-8. [2]. Avinash VS, et al. Penicillin acylases revisited: importance beyond their industrial utility. Crit Rev Biotechnol. 2016;36(2):303-16. [3]. Tishkov VI, et al. Protein engineering of penicillin acylase. Acta Naturae. 2010 Jul;2(3):47-61. |