| Bioactivity | Pegtarazimod (RLS-0071) is an inhibitor for Complement system via classical and lectin pathways. Pegtarazimod inhibits myeloperoxidase (MPO), reduces ROS generation. Pegtarazimod reduces the formation of neutrophil extracellular traps (NETs). Pegtarazimod exhibits anti-inflammatory activity and can be used in research of acute graft-versus-host disease[1]. |
| CAS | 2056232-82-5 |
| Sequence | Ile-Ala-Leu-Ile-Leu-Glu-Pro-Ile-Cys-Cys-Gln-Glu-Arg-Ala-Ala-PEG24 |
| Shortening | IALILEPICCQERAA-PEG24 |
| Formula | C122H224N20O46S2 |
| Molar Mass | 2771.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Holzmüller V, et al. Exploring a Novel Anti-Inflammatory Peptide As a Potential Treatment for Acute Graft-Versus-Host Disease (aGVHD)[J]. Blood, 2024, 144: 3399. |
Pegtarazimod
CAS: 2056232-82-5 F: C122H224N20O46S2 W: 2771.32
Pegtarazimod (RLS-0071) is an inhibitor for Complement system via classical and lectin pathways. Pegtarazimod inhibits m
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.