Bioactivity | Pegmolesatide(HS-20039; EPO-018B) a synthetic peptide-based erythropoiesis-stimulating agent, can be used for ??the study of anemia in chronic kidney disease[1]. |
Name | Pegmolesatide |
CAS | 2420483-81-2 |
Sequence | PEGn-Chain1:Gly-Gly-Thr-Tyr-Ser-Cys-His-Phe-Gly-Ala-Leu-Thr-Trp-Val-Cys-Arg-Pro-Gln-Arg-Gly-{Bal}-Lys-NH2 (Disulfide bridge:Cys6-Cys15); Chain2:Gly-Gly-Thr-Tyr-Ser-Cys-His-Phe-Gly-Ala-Leu-Thr-Trp-Val-Cys-Arg-Pro-Gln-Arg-Gly-{Bal}-Lys-NH2 (Disulfide bridge:Cys6-Cys15); Chain3:Lys-{Bal}-Gly (Amide bridge:Chain1 Lys22-Chain Gly3; Covalent bridge:Chain Lys22-Chain3 Gly3) |
Shortening | PEGn-Chain1:GGTYSCHFGALTWVCRPQRG-{Bal}-K-NH2 (Disulfide bridge:Cys6-Cys15); Chain2:GGTYSCHFGALTWVCRPQRG-{Bal}-K-NH2 (Disulfide bridge:Cys6-Cys15); Chain3:K-{Bal}-G (Amide bridge:Chain1 Lys22-Chain Gly3; Covalent bridge:Chain Lys22-Chain3 Gly3) |
Formula | (C2H4O)n(C2H4O)nC231H344N72O64S4 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. J. CHEN, et al. POS-606 Pegmolesatide for the treatment of anemia in CKD patients undergoing dialysis: Interim analysis of a multicenter phase Ⅲ trial. ABSTRACT, VOLUME 7, ISSUE 2, SUPPLEMENT , S260, FEBRUARY 2022 |