| Bioactivity | Pedunculagin is a potent 5α-reductase type 1 inhibitor. Pedunculagin inhibits nitric oxide (NO), IL-6, IL-8 production. Pedunculagin decreases the protein expression of 5α-reductase. Pedunculagin shows anti-inflammatory activity[1]. |
| Invitro | Pedunculagin 在 RAW 246.7 细胞 中抑制一氧化氮 (NO) 的产生，IC50 值为 53.52 µM[1]。Pedunculagin 在 HaCaT 细胞中抑制 IL-6、IL-8 的产生，IC50 分别为 6.59、0.09 µM[1]。Pedunculagin (25, 50, 100 µM; 24 h) 降低 HaCaT 细胞中 5α-还原酶的蛋白表达[1]。 Western Blot Analysis[1] Cell Line: |
| Name | Pedunculagin |
| CAS | 113866-64-1 |
| Formula | C41H28O26 |
| Molar Mass | 936.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kim M, et al. Anti-Acne Vulgaris Effects of Pedunculagin from the Leaves of Quercus mongolica by Anti-Inflammatory Activity and 5α-Reductase Inhibition. Molecules. 2020 May 5;25(9):2154. |
Pedunculagin
CAS: 113866-64-1 F: C41H28O26 W: 936.65
Pedunculagin is a potent 5α-reductase type 1 inhibitor. Pedunculagin inhibits nitric oxide (NO), IL-6, IL-8 production.
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This product is for research use only, not for human use. We do not sell to patients.