| Bioactivity | Patuletin is a flavonol, that can be isolated from the flowers of Tagetes patula. Patuletin shows anti-proliferative activity against cancer cells. Patuletin causes significant nuclear fragmentation and has a great capacity to induce caspase-3 activation[1][2]. |
| Invitro | Patuletin (0-100 μg/mL，24 h) 具有抗癌细胞增殖活性[2]。Patuletin 可诱导 CaSki、MDA-MB-231 和 SK-Lu-1 细胞凋亡[2]。 0 --> Patuletin 相关抗体: Cell Proliferation Assay[2] Cell Line: |
| Name | Patuletin |
| CAS | 519-96-0 |
| Formula | C16H12O8 |
| Molar Mass | 332.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zane A , et al. Flavonols in Spinach Leaves[J]. Journal of Organic Chemistry, 1961, 26(11). [2]. Alvarado-Sansininea JJ, et al. Quercetagetin and Patuletin: Antiproliferative, Necrotic and Apoptotic Activity in Tumor Cell Lines. Molecules. 2018 Oct 9;23(10):2579. |