Bioactivity | Pateclizumab (MLTA3698A) is a humanized antibody against lymphotoxin α (LTα), a transiently expressed cytokine on activated B and T cells (Th1, Th17), which are implicated in rheumatoid arthritis (RA) pathogenesis[1]. |
Target | lymphotoxin α |
Name | Pateclizumab |
CAS | 1202526-59-7 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Brinda Emu, et al. Safety, pharmacokinetics, and biologic activity of pateclizumab, a novel monoclonal antibody targeting lymphotoxin α: results of a phase I randomized, placebo-controlled trial. |