| Bioactivity | Pascolizumab (SB-240683) is a humanized anti-IL-4 monoclonal antibody. Pascolizumab has the potential for the research of asthma[1]. |
| Invitro | Pascolizumab 结合 IL-4 可抑制 IL-4 与 IL-4 受体的 α 链相互作用[1]。Pascolizumab (0-10000 pM; 3 days) 显示出抗增殖活性，对 T 细胞和扁桃体 B 细胞的 IC50 值分别为 157、377 pM[1]。 Cell Proliferation Assay[1] Cell Line: |
| Name | Pascolizumab |
| CAS | 331243-22-2 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hart TK, et al. Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma. Clin Exp Immunol. 2002 Oct;130(1):93-100. |