| Bioactivity | Pantothenate kinase-IN-2 is a potent Pantothenate kinase 1/3 (PanK1/3) inhibitor with an IC50 of 0.14 μM and 0.36 μM. Pantothenate kinase-IN-2 is a promising agent for PKAN (PanK-associated neurodegeneration) and diabetes research[1]. | ||||||||||||
| Target | IC50: 0.14 μM (PanK1); 0.36 μM (PanK3) | ||||||||||||
| Name | Pantothenate kinase-IN-2 | ||||||||||||
| CAS | 902614-04-4 | ||||||||||||
| Formula | C21H21N5OS | ||||||||||||
| Molar Mass | 391.49 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Lalit Kumar Sharma, et al. A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases. J Med Chem. 2015 Feb 12;58(3):1563-8. |
Pantothenate kinase-IN-2
CAS: 902614-04-4 F: C21H21N5OS W: 391.49
Pantothenate kinase-IN-2 is a potent Pantothenate kinase 1/3 (PanK1/3) inhibitor with an IC50 of 0.14 μM and 0.36 μM.
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