| Bioactivity | Pantothenate kinase-IN-1 (Compound 1) is a pantothenate kinase (PANK) modulator with an IC50 of 0.51 µM against PANK3. Pantothenate kinase-IN-1 has a reasonable ligand efficiency (LipE = 2.8)[1]. |
| Target | IC50: 0.51 µM (PANK3) |
| Name | Pantothenate kinase-IN-1 |
| CAS | 1024168-48-6 |
| Formula | C21H25N5O |
| Molar Mass | 363.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sharma LK, et al. LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators. Bioorg Med Chem. 2021 Dec 15;52:116504. |