| Bioactivity | Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively[1]. |
| CAS | 1224691-12-6 |
| Formula | C19H24N2O6 |
| Molar Mass | 376.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ruan BH, et al. A fluorescent assay suitable for inhibitor screening and vanin tissue quantification. Anal Biochem. 2010 Apr 15;399(2):284-92. |
Pantothenate-AMC
CAS: 1224691-12-6 F: C19H24N2O6 W: 376.40
Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in
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