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Pancreatic lipase/Carboxylesterase 1-IN-1

CAS: 194235-21-7 F: C30H44O4 W: 468.67

Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of pancreatic lipase (PL) and human c
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Bioactivity Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A) with IC50 values of 2.13 µM and 0.055  µM against PL and hCES1A[1].
Target IC50: 0.055  µM (hCES1A), 2.13 µM (PL), 6.02 µM (hCES2A)
Name Pancreatic lipase/Carboxylesterase 1-IN-1
CAS 194235-21-7
Formula C30H44O4
Molar Mass 468.67
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Zhang J, et al. Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1. J Enzyme Inhib Med Chem. 2022 Dec;37(1):629-640.