| Bioactivity | Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities[1][2]. | ||||||||||||
| Invitro | Panaxadiol (1-10 μM, 12 h) inhibits PD-L1 expression in human colon cancer cells[1].Panaxadiol (1-10 μM, 12 h) inhibits the expression of PD-L1 by suppressing HIF-1α and STAT3 in HCT116 cells[1]. Western Blot Analysis[1] Cell Line: | ||||||||||||
| Name | Panaxadiol | ||||||||||||
| CAS | 19666-76-3 | ||||||||||||
| Formula | C30H52O3 | ||||||||||||
| Molar Mass | 460.73 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
Panaxadiol
CAS: 19666-76-3 F: C30H52O3 W: 460.73
Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 the
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.