| Bioactivity | Pan-rasin-2 (compound 6A) is a molecular glues that targets RAS. Pan-rasin-2 has significant inhibitory activity on cell proliferation of RAS mutant cell lines. Pan-rasin-2 can form ternary complexes with cyclophilin A (CYPA) and RAS (ON) proteins and the formation of ternary complexes can block the binding of RAF downstream of RAS, which has anti-tumor effects[1]. |
| CAS | 3034673-92-9 |
| Formula | C46H60N8O5S |
| Molar Mass | 837.08 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Y Zhang, et al. Macrocyclic derivative and use thereof. WO2024067857A1. 2023-09-28 |
Pan-RAS-IN-2
CAS: 3034673-92-9 F: C46H60N8O5S W: 837.08
Pan-rasin-2 (compound 6A) is a molecular glues that targets RAS. Pan-rasin-2 has significant inhibitory activity on cell
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.