| Bioactivity | Pamidronate disodium (Standard) is the analytical standard of Pamidronate disodium.Pamidronate disodium (Standard), the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium (Standard) significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of OPG in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium (Standard) can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma. |
| CAS | 57248-88-1 |
| Formula | C3H9NNa2O7P2 |
| Molar Mass | 279.03 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Pamidronate (disodium) (Standard)
CAS: 57248-88-1 F: C3H9NNa2O7P2 W: 279.03
Pamidronate disodium (Standard) is the analytical standard of Pamidronate disodium.Pamidronate disodium (Standard), the
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