Palmitoyl serotonin_product_DataBase

Bioactivity	Palmitoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin, antagonist of FAAH. Palmitoyl serotonin inhibits L-3,4-dihydroxyphenylalanine (HY-N0304) induced abnormal involuntary movements. Palmitoyl serotonin has the potential for the research of parkinson's disease (PD)[1][2].
In Vivo	Palmitoyl serotonin ( 0.3 mg/kg; daily for 10 days) 可有效减轻左旋多巴诱导的运动障碍 (LID) 的发展，并增加半侧帕金森病小鼠模型中 ERK1/2 磷酸化和 FosB/ΔFosB 表达[ 1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	212707-51-2
Formula	C26H42N2O2
Molar Mass	414.62
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Park HY, et al. Palmitoyl Serotonin Inhibits L-dopa-induced Abnormal Involuntary Movements in the Mouse Parkinson Model. Exp Neurobiol. 2016 Aug;25(4):174-84. [2]. Muthubharathi BC, et al. Physiological and Metabolite Alterations Associated with Neuronal Signals of Caenorhabditis elegans during Cronobacter sakazakii Infections. ACS Chem Neurosci. 2021 Nov 17;12(22):4336-4349.

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