| Bioactivity | Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity[1][2][3]. | ||||||||||||
| Invitro | Paeoniflorin (80 μg/mL; 4-24 h) treatment can induce Hsp40 and Hsp27 as well as Hsp70[3]. Western Blot Analysis[3] Cell Line: | ||||||||||||
| In Vivo | Paeoniflorin (intradermal injection; 25 and 100mg/kg; once daily; 20 days) shows favorable effects on experimental arthritis[4]. Animal Model: | ||||||||||||
| Name | Paeoniflorin | ||||||||||||
| CAS | 23180-57-6 | ||||||||||||
| Formula | C23H28O11 | ||||||||||||
| Molar Mass | 480.46 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Yan-Xi Zhou, et al. A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects. Biomed Pharmacother. 2020 Oct;130:110505. [2]. Yongjing Xiang, et al. Paeoniflorin: a monoterpene glycoside from plants of Paeoniaceae family with diverse anticancer activities. J Pharm Pharmacol. 2020 Apr;72(4):483-495. [3]. Dai Yan, et al. Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones. 2004 Winter;9(4):378-89. Int J Oncol. 2013 Nov;43(5):1643-51. [4]. Pei-Pei Li, et al. BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin. J Ethnopharmacol. 2012 May 7;141(1):290-300. |
Paeoniflorin
CAS: 23180-57-6 F: C23H28O11 W: 480.46
Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with var
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