Bioactivity | Pacritinib (Standard) is the analytical standard of Pacritinib. This product is intended for research and analytical applications. Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). Pacritinib also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). |
CAS | 937272-79-2 |
Formula | C₂₈H₃₂N₄O₃ |
Molar Mass | 472.58 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |