| Bioactivity | Paclitaxel ceribate is the ester form of paclitaxel, a natural antineoplastic agent that stabilizes tubulin polymerization. Paclitaxel causes mitotic arrest and induces apoptosis, ultimately leading to cell death. Paclitaxel also induces autophagy[1][2]. |
| CAS | 186040-50-6 |
| Formula | C51H57NO18 |
| Molar Mass | 971.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Choi YH, et al. Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells. Oncol Rep. 2012 Dec;28(6):2163-9. [2]. Dziadyk JM, et al. Paclitaxel-induced apoptosis may occur without a prior G2/M-phase arrest. Anticancer Res. 2004 Jan-Feb;24(1):27-36. |
Paclitaxel ceribate
CAS: 186040-50-6 F: C51H57NO18 W: 971.99
Paclitaxel ceribate is the ester form of paclitaxel, a natural antineoplastic agent that stabilizes tubulin polymerizati
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