| Bioactivity | Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy[1]. |
| CAS | 245110-80-9 |
| Formula | C55H58N2O19 |
| Molar Mass | 1051.05 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dosio F, et al. Novel nanoassemblies composed of squalenoyl− paclitaxel derivatives: synthesis, characterization, and biological evaluation[J]. Bioconjugate chemistry, 2010, 21(7): 1349-1361. |
Paclitaxel-2′-succinate NHS ester
CAS: 245110-80-9 F: C55H58N2O19 W: 1051.05
Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group i
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